Scleroderma causes the skin to become tight and shiny due to excessive collagen production. Localized scleroderma, or morphea, only involves the skin and usually does not affect internal organs.

There are two main categories of scleroderma: localized and systemic. Each category is made up of several conditions. Localized scleroderma: often affects only the skin and not major organs. Systemic ...

The aim of this Cochrane Review was to assess the effects of treatments, either given in isolation or combination, for people with morphea (morphoea), when compared with an inactive substance (placebo ...

If you click on links we provide, we may receive compensation. The actor and comedian's memoir 'Actress of a Certain Age' is out now Ilana Kaplan is a Staff Editor at PEOPLE. She has been working at ...

HSS is the #1 orthopedic hospital in the U.S. and a national leader in rheumatology. This content was created by our physicians and experts. By Jessica K. Gordon, MD; Kimberly (Showalter) Lakin, MD, ...

Living with a rare condition that causes visible symptoms can be mentally and physically challenging. Not only that, but people are sometimes subjected to cruel comments about something beyond their ...

Scleroderma on the face can cause symptoms that may affect your appearance, including the texture, discoloration, and elasticity of your skin. Medications, facial exercises, and dermatological ...

Morphea, also known as localized scleroderma, is a rare, commonly misdiagnosed, sclerosing disease. Linear morphea is the most common subtype in children.1, 2 In the inflammatory stage, an ...

Most people with scleroderma have autoantibodies. Several scleroderma-specific antibodies have been identified. These can help with diagnosis and give insight into the type of disease you may ...

Scleroderma is a disease of the immune system that scars and thickens the skin. Sometimes it damages the area around internal organs and blood vessels. It varies in severity from a mild form that most ...