The formation of the neuromuscular junction (NMJ) is directed by reciprocal interactions between motor neurons and muscle fibers. Neuregulin (NRG) and Agrin from motor nerve terminals are both ...

In a serendipitous discovery, UC San Diego researchers using cryo-EM technology captured the first visualizations of the 3-D structure of the muscle acetylcholine receptor in fetal and adult muscles.

Scattered throughout skeletal muscle, the muscle spindles are composed of connective tissue capsules containing bundles of specialized muscle fibers called intrafusal fibers. Wrapped around the middle ...

While NGF can be detected in periosteal osteoprogenitor cells in intact bone, NGF protein has also been detected in osteoprogenitor cells, marrow stromal cells, osteoblasts, some chondrocytes, ...

Skeletal muscle is the type of muscle that controls movement. Problems with these muscles can be minor, life-threatening, or ongoing problems that make it hard to perform basic daily activities.

During restricted periods of development (embryonic day (E) 14.5-E15.5 in mice 1), peripheral innervation of a subset of type I myotubes by group Ia sensory (but not motor 9) axons provides ...

Researchers confirm and explore the role of estrogen-related receptors in regulating energy production in muscle cells during exercise. The findings indicate that developing a drug to boost ...

Using powerful new visualization technologies, researchers have captured the first 3-D images of the structure of a key muscle receptor, providing new insights on how muscles develop across the animal ...