Prospective Validation Study in JAAD Demonstrates Castle Biosciences’ AdvanceAD-Tx™ Test Identifies Patients More Likely to Achieve Faster and Deeper Responses with JAK ...

Achieve near-complete or complete skin clearance, as reflected by a Validated Investigator Global Assessment score of clear (vIGA-AD 0, 36.4% vs 0%, p=0.006) Report higher rates of “no itch” (45.5% vs ...
The Manila Times

Prospective Validation Study in JAAD Demonstrates Castle Biosciences’ AdvanceAD-Tx™ Test Identifies Patients More Likely to Achieve Faster and Deeper Responses with JAK ...

Study data show that AdvanceAD-Tx can stratify patients by molecular profile identifying those more likely to achieve near-clear skin (EASI-90), faster time to response and meaningful patient-reported ...
eLife

Juvenile reinstatement of TCF4 in Pitt-Hopkins syndrome model mice reveals a critical window for genetic intervention

This is an important study that identifies the developmental time window during which re-expression of TCF4 mutated in Pitt-Hopkins syndrome, can rescue phenotypic features of brain function in a TCF4 ...

A new method to decode how DNA 'switches' control gene activity

DNA is the blueprint of life. Genes encode proteins and serve as the body's basic components. However, building a functioning ...

Tempus AI Stock Jumps As Mizuho Starts Coverage, Earnings Scheduled For Next Week

Tempus AI shares climb after Mizuho's Outperform call and a new HRD-RNA cancer detection algorithm announcement.

Merlin CP-GEP Becomes the First and Only Gene Expression Profile (GEP) Test Recommended by NCCN® Cutaneous Melanoma Guidelines to Assess Metastatic Risk

SkylineDx today announced that the National Comprehensive Cancer Network® (NCCN®) has updated its Clinical Practice Guidelines in Oncology for Cutaneous Melanoma (Version 1.2026), recognizing Merlin ...
Frontiers

Sex as a biological variable in the neurocircuitry of motivated behavior

It is generally assumed that differences in the processing of salient information and the manifestation of motivated behavior are a product of variations in neurocircuitry. The contribution of sex to ...