In 1997, Alan Leshner, then director of the National Institute for Drug Abuse, wrote an article entitled “Addiction Is a Brain Disease and It Matters.” That eight-word title became the perfect sound ...

Is addiction a disease? Do the kids I work with at CASTLE have a pathological response to drugs and alcohol? The disease model of addiction is compelling, and has served its purpose in bringing needed ...

January is Substance Use Disorder Treatment Month, which is designed to raise awareness about those suffering with substance ...

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With the opioid epidemic reaching into every corner of the U.S., more people are talking about addiction as a chronic disease rather than a moral failing. For researcher A. Thomas McLellan, who has ...

Methamphetamine doesn't just spike levels of the pleasure-inducing hormone dopamine in the reward pathways of the brain—it also provokes damaging brain inflammation through similar mechanisms.

Methamphetamine addiction has a way of looping back on itself. A rush of pleasure pulls you in, cravings follow, and the brain learns that the drug is the fastest route to reward. Yet scientists still ...