Andrés Aguilera's laboratory, in collaboration with that of Ralf Wellinger (both professors in the Department of Genetics at the University of Seville in CABIMER) and with PharmaMAR, has identified ...
New Cornell research is providing a fresh view into the ways a common chemotherapy agent, etoposide, stalls and poisons the essential enzymes that allow cancer cells to flourish. The findings, from ...
New research is providing a fresh view into the ways a common chemotherapy agent, etoposide, stalls and poisons the essential enzymes that allow cancer cells to flourish. New Cornell research is ...
Bacterial topoisomerase inhibitors represent a promising class of antimicrobial agents that target essential enzymes involved in DNA replication and maintenance. By inhibiting enzymes such as DNA ...
A series of experiments reveal that a germline mutation of the enzyme topoisomerase II B affects the movement of proteins in the nuclei of cells with this mutation The processes of DNA replication and ...
The solution to DNA's topological problems comes in the form of enzymes called topoisomerases that serve as "swivels" and allow the molecule to perform its requisite acrobatics. Type I topoisomerase ...
This is a preview. Log in through your library . Abstract Topological entanglements severely interfere with important biological processes. For this reason, genomes must be kept unknotted and unlinked ...
A Dutch led international team of researchers has unravelled how nature releases the torque built up in DNA at the molecular level. The researchers from Delft University of Technology, the Ecole ...
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